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Activin antagonists as novel contraceptives

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Sefer Yesira

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The contraceptive agent results in inhibition of the activin-stimulated re-lease of FSH, thereby resulting in a de-crease in fertility and facilitating contra-ception in the patient. This invention relates to contraception. The biosyntllesis and secretion of 15 FSH within the anterior pituitary is controlled through the complex interaction of several h- -.

Inhibin And follistatin have the ability to inhibit the synthesis and secretion of FSH by the pituitary De Jong et al. Both activin and inhibin subunits have been isolated from natural sources. In Mason et al. The use of activin to increase fertility in a male mammal is described in Attie et al. Following treatment of rat testicular germ cells with activin, these cells were observed to proliferate 2.

R-secreted activin Weiss et al. In 30 a particular: In yet another preferred: Activin-stimulated relea6e of FSH can be inhibited by a number of dif f erent – i. These factors would be rapidly removed from perifusion columns but appear to A:

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Likewise, various other means of eoolii-ig the body have bcen tried with coolin; blwikcts, ice waterbla. All of thcsc dcvices requirc a considcrable time to cool the body sin. A more efficicnt body cooling device that can quickly cool and accurately control the body temperature is required. The systemic approach is not always advantageous when the beneficial effects are desired locally at the focus o.

More recent focus has been directed to producing hypothermia in localized areas of ihe body, teavina lhe remainder of the body to function at a non-nal body tcinipcraturc. Thcsc localizcd applications of hyhotllcrrnia havc hccn cxtcrnal, rc]ying for cxample on cooling helmets or cooling ncck collars to produce localizcd hypothermia for the brain.

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These exemptions will apply until December 31, unless we cease to qualify as an emerging growth company prior to that date. You may also access the above off-site website by going to www. When is the Annual Meeting? May 18, at To elect four persons to serve as directors of the Company until the Annual Meeting of Shareholders or until their successors are duly elected and qualified. To consider such other business as may properly come before the Annual Meeting or any adjournment thereof.

The Board is not aware of any other business to be conducted at the Annual Meeting. On the Record Date, there were 6, , shares of common stock outstanding and entitled to vote and approximately beneficial owners, including approximately shareholders of record. There is no other class of voting stock outstanding. How do I vote by proxy?

The Ohio State news (Columbus, Ohio), 1946-05-25, LOCAL EDITION

Rt T,nt-, place; the country around is toio n;f it r,oK v.. IU ‘ restrain them, the great European powers arc still endeavoring to induce the Sultanc to accept the original note of the Yienna Con- ference The announcement of the defection, of Aus- tria has seriously aflectud the -money market generally. Vn inn n 10 nnnr nrttrt Columbia-Bill Pedlcrs, are longing for some ” live oaljfctreat,” like that spokea of by Koms,” where tlmy”can retire andnpoze until something turnTtip.

The cbolera is ravaging the north of Eu- rope to a fearful extent. ICorreejfOailonc of the foluaibia Democrat.

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This book may not be reproduced, in whole or in part, in any form beyond that permitietl by copyright law without the publisher’s writtcn permission. The fluid state of the text of Sefer Yesira. Why a new edition of Sefer Yesira’? The “original text” of SY or “the earliest recoverable text”? Editing Jewish texts from the first millennium C.

The rules of the edition. Notes on the manuscripts. The Chapter and Paragraph Divisions Appendix The Four Pre-Kabbalistic Cornnielltaries.

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The Rabbis then instituted that the Shema should be recited before the regular Morning Prayer. dating back to Talmudic times. before its regular recitation in the blessing of Yotzer. (When Mzlsaf is ://

Likewise, various other means of eoolii-ig the body have bcen tried with coolin; blwikcts, ice waterbla. All of thcsc dcvices requirc a considcrable time to cool the body sin. A more efficicnt body cooling device that can quickly cool and accurately control the body temperature is required. The systemic approach is not always advantageous when the beneficial effects are desired locally at the focus o.

More recent focus has been directed to producing hypothermia in localized areas of ihe body, teavina lhe remainder of the body to function at a non-nal body tcinipcraturc. Thcsc localizcd applications of hyhotllcrrnia havc hccn cxtcrnal, rc]ying for cxample on cooling helmets or cooling ncck collars to produce localizcd hypothermia for the brain. Summary of the Invention A heat excliange catheter and rnethod of operation are itichtded in the prescnt S.

The selected body portion will usullly be associated with a body conduit which conveys a body fluid to the selected body portion. Of particular interest are the organs of the body which are comrnonly nourished and maintained by a flow of blood in the arterial systein. For example, a flow of blood is introduccd to thc brain througli the carotid artery.

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